LTC4S ELISA Kit for Human(Homo sapiens) | EIAab.comLTC4S ELISA Kit for Human(Homo sapiens)

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Index > Protein center > LTC4S(Gene name) > Human

LTC4S (Gene name),

Leukotriene C4 synthase (Protein name ), LTC4S_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

LTC4S;

Protein name:

Leukotriene C4 synthase(LTC4 synthase);

Alternative:

Leukotriene-C(4) synthase;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homotrimer. Interacts with ALOX5AP and ALOX5.

Function:

Catalyzes the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4.

Subcellular Location:

Nucleus outer membrane Multi-pass membrane protein Endoplasmic reticulum membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

150

Sequence:

50:

100:

150:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

246530

KEGG:

hsa:4056

STRING:

9606.ENSP00000292596

String:

Q16873

Pfam:

PF01124

SMR:

Q16873

UniGene:

Hs.706741

Uniprot:

Q16873

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ELISA Kit for Human LTC4 synthase

Cat.:

E10100h

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Packing:

96T

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ELISA Kit for Human LTC4 synthase

Cat.:

E10100b

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96T

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ELISA Kit for Human LTC4 synthase

Cat.:

E10100m

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96T

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ELISA Kit for Human LTC4 synthase

Cat.:

E10100r

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96T

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CLIA Kit for Human LTC4 synthase

MSDS:

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CLIA Kit for Human LTC4 synthase

Cat.:

U10100m

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Packing:

96T

CLIA Kit for Human LTC4 synthase

Cat.:

U10100h

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Packing:

96T

CLIA Kit for Human LTC4 synthase

Cat.:

U10100r

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Packing:

96T

Polyclonal Antibody for Human LTC4 synthase

Cat.:

P10100Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human LTC4 synthase

Monoclonal Antibody for Human LTC4 synthase

Protein for Human LTC4 synthase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Expression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4."
Lam B.K. , Penrose J.F. , Freeman G.J. , Austen K.F.
Proc. Natl. Acad. Sci. U.S.A.91:7663-7667(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 1-22 AND 35-48
tissue: Bone marrow.
2.

"Molecular cloning and expression of human leukotriene-C4 synthase."
Welsch D.J. , Creely D.P. , Hauser S.D. , Mathis K.J. , Krivi G.G. , Isakson P.C.
Proc. Natl. Acad. Sci. U.S.A.91:9745-9749(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Molecular cloning of the gene for human leukotriene C4 synthase. Organization, nucleotide sequence, and chromosomal localization to 5q35."
Penrose J.F. , Spector J. , Baldasaro M. , Xu K. , Boyce J. , Arm J.P. , Austen K.F. , Lam B.K.
J. Biol. Chem.271:11356-11361(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Molecular cloning of the human leukotriene C4 synthase gene and assignment to chromosome 5q35."
Bigby T.D. , Hodulik C.R. , Arden K.C. , Fu L.
Mol. Med.2:637-646(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT GLN-142
tissue: Brain.
6.

"Purification to homogeneity and the N-terminal sequence of human leukotriene C4 synthase: a homodimeric glutathione S-transferase composed of 18-kDa subunits."
Nicholson D.W. , Ali A. , Vaillancourt J.P. , Calaycay J.R. , Mumford R.A. , Zamboni R.J. , Ford-Hutchinson A.W.
Proc. Natl. Acad. Sci. U.S.A.90:2015-2019(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-35
7.

"Purification of human lung leukotriene C4 synthase and preparation of a polyclonal antibody."
Penrose J.F. , Spector J. , Lam B.K. , Friend D.S. , Xu K. , Jack R.M. , Austen K.F.
Am. J. Respir. Crit. Care Med.152:283-289(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-19;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
tissue: Lung.
8.

"Two step purification of human and murine leukotriene C4 synthase."
Goppelt-Struebe M.
Biochim. Biophys. Acta1256:257-261(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-17
tissue: Monocyte.
9.

"Leukotriene C4-synthesis deficiency: a new inborn error of metabolism linked to a fatal developmental syndrome."
Mayatepek E. , Flock B.
Lancet352:1514-1517(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN LTC4 SYNTHASE DEFICIENCY
10.

"Defects in the synthesis of cysteinyl leukotrienes: a new group of inborn errors of metabolism."
Mayatepek E. , Zelezny R. , Lehmann W.D. , Hammond J.W. , Hoffmann G.F.
J. Inherit. Metab. Dis.23:404-408(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN LTC4 SYNTHASE DEFICIENCY
11.

"Membrane localization and topology of leukotriene C4 synthase."
Christmas P. , Weber B.M. , McKee M. , Brown D. , Soberman R.J.
J. Biol. Chem.277:28902-28908(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TOPOLOGY
12.

"Distinct parts of leukotriene C(4) synthase interact with 5-lipoxygenase and 5-lipoxygenase activating protein."
Strid T. , Svartz J. , Franck N. , Hallin E. , Ingelsson B. , Soederstroem M. , Hammarstroem S.
Biochem. Biophys. Res. Commun.381:518-522(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ALOX5AP AND ALOX5;SUBCELLULAR LOCATION
13.

"Crystal structure of a human membrane protein involved in cysteinyl leukotriene biosynthesis."
Ago H. , Kanaoka Y. , Irikura D. , Lam B.K. , Shimamura T. , Austen K.F. , Miyano M.
Nature448:609-612(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS) IN COMPLEX WITH GLUTATHIONE;ACTIVE SITE;TOPOLOGY;SUBUNIT
14.

"Structural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase."
Martinez Molina D. , Wetterholm A. , Kohl A. , McCarthy A.A. , Niegowski D. , Ohlson E. , Hammarberg T. , Eshaghi S. , Haeggstroem J.Z. , Nordlund P.
Nature448:613-616(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 2-150 IN COMPLEX WITH GLUTATHIONE;SUBUNIT;TOPOLOGY

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